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Invitrogen
SH3RF1 Monoclonal Antibody (K1E030_5E8)
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SH3RF1 Antibody (MA5-55676) in WB
Western blot analysis of SH3RF1 in 15 µg of mouse brain tissue lysate. Sample was run on 6-18% SDS-PAGE under reducing conditions, blotted onto nitrocellulose membrane, and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. SH3RF1 band was visualized using ECL Western Blotting Substrate. Incubation with primary SH3RF1 monoclonal antibody (Product # MA5-55676) at a dilution of 1 µg/mL was used.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-55676
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
K1E030_5E8
抗原
Recombinant human SH3RF1 (immunogen range is 701-880).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Sequence of this protein is as follows: GNSSATKPDK DSKKEKKGLL KLLSGASTKR KPRVSPPASP TLEVELGSAE LPLQGAVGPE LPPGGGHGRA GSCPVDGDGP VTTAVAGAAL AQDAFHRKAS SLDSAVPIAP PPRQACSSLG PVLNESRPVV CERHRVVVSY PPQSEAELEL KEGDIVFVHK KREDGWFKGT LQRNGKTGLF
靶标信息
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ21602; plenty of SH3 domains; plenty of SH3s; putative E3 ubiquitin-protein ligase SH3RF1; ring finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2; SH3-containing adaptor molecule; unnamed protein product
基因别名: 2200003J05Rik; POSH; RNF142; SH3MD2
UniProt ID: (Human) Q7Z6J0, (Mouse) Q69ZI1
Entrez Gene ID: (Human) 57630, (Mouse) 59009
MAPK cascade
neuron migration
protein ubiquitination
negative regulation of apoptotic process
regulation of CD4-positive, alpha-beta T cell differentiation
positive regulation of JNK cascade
protein autoubiquitination
response to aldosterone
regulation of CD8-positive, alpha-beta T cell proliferation
negative regulation of extrinsic apoptotic signaling pathway
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