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SIGLEC5 Monoclonal Antibody (1A5), APC
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产品信息
MA574224
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A5
抗原
Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1.
偶联物
APC
APC
APC
激发/发射光谱
651/660 nm
查看光谱
形式
Liquid
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
15mM sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
SIGLEC5 (CD170) is a member of the sialic acid-binding immunoglobulin-like lectin family expressed mainly on myeloid cells such as neutrophils and monocytes. It functions as an inhibitory receptor that recognizes sialylated glycans and transduces signals through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, helping regulate innate immune responses and dampen inflammation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD170; CD33 antigen-like 2; OB-BP2; Obesity-binding protein 2; Sialic acid-binding Ig-like lectin 5; Siglec-5
基因别名: CD33L2; OBBP2; SIGLEC5
Entrez Gene ID: (Human) 8778
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