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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
MA5-17174 targets SKP1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17174 immunogen is purified recombinant fragment of human SKP1 expressed in E. Coli.
MA5-17174 detects SKP1 which has a predicted molecular weight of approximately 19kDa.
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteasome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cyclin-A/CDK2-associated protein p19; MGC34403; OCP-2; OCP-II; OCP-II protein; Organ of Corti protein 2; Organ of Corti protein II; p19A; p19skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; S-phase kinase-associated protein 1; SIII; Transcription elongation factor B polypeptide 1-like
基因别名: EMC19; OCP2; SKP1; SKP1A; TCEB1L
Entrez Gene ID: (Human) 6500