Abnova

SLAMF6 Polyclonal Antibody, MaxPab™

Name: SLAMF6 Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00114836-B01P

查看其他35个Ly-108抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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SLAMF6 Antibody (H00114836-B01P) in WB

Western Blot analysis of SLAMF6 expression in transfected 293T cell line by SLAMF6 MaxPab polyclonal antibody. Lane 1: SLAMF6 transfected lysate(29.81 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00114836-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

SLAMF6 (AAH90928.1, 1 a.a. approximately 271 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MLWLFQSLLF VFCFGPGNVV SQSSLTPLMV NGILGESVTL PLEFPAGEKV NFITWLFNET SLAFIVPHET KSPEIHVTNP KQGKRLNFTQ SYSLQLSNLK MEDTGSYRAQ ISTKTSAKLS SYTLRILRQL RNIQVTNHSQ LFQNMTCELH LTCSVEDADD NVSFRWEALG NTLSSQPNLT VSWDPRISSE QDYTCIAENA VSNLSFSVSA QKLCEDVKIQ YTDTKMILFM VSGICIVFGF IILLLLVLRK RRDSLSLSTQ RTQGPGEHSD S

靶标信息

Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。