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Invitrogen
SLC13A3 Polyclonal Antibody
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SLC13A3 Antibody (PA5-110375) in WB
Western blot analysis of SLC13A3 in extracts of various cell lines. Samples were incubated with SLC13A3 Polyclonal antibody (Product # PA5-110375) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-110375
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 160-240 of human SLC13A3 (NP_073740.2).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.45 mg/mL
规格
145 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KSLFGQKEVR KDPSQESEEN TAAVRRNGLH TVPTEMQFLA STEAKDHPGE TEVPLDLPAD SRKEDEYRRN IWKGFLISIP Y
靶标信息
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hNaDC3; membrane transporter responsible for the transport of tricarboxylic acid cycle intermediates; Na(+)-coupled carboxylate transporter 3; naDC-3; NADC3; integral membrane transporter; sodium-dependent high affinity dicarboxylate transporter 3; unnamed protein product
基因别名: ARLIAK; NaC3; NADC3; SDCT2
UniProt ID: (Human) Q8WWT9
Entrez Gene ID: (Human) 64849
dicarboxylic acid transmembrane transporter activity
protein binding
citrate transmembrane transporter activity
alpha-ketoglutarate transmembrane transporter activity
succinate transmembrane transporter activity
high-affinity sodium:dicarboxylate symporter activity
solute:sodium symporter activity
sodium:dicarboxylate symporter activity
transmembrane transporter activity
glutathione transmembrane transporter activity
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