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Invitrogen
SLC25A33 Polyclonal Antibody
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产品信息
PA5-21793
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human SLC25A33. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (87%), Rat (88%), Sheep (97%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The SLC25A33 gene belongs to the solute carrier family 25 (SLC25), which is the largest family of mitochondrial transport proteins comprising 53 members. The SLC25A33 gene encodes a mitochondrial transporter responsible for the transport of pyrimidine nucleotides, specifically deoxyadenine nucleotides, across the inner mitochondrial membrane. This transport is crucial for nucleotide salvage pathways, ensuring the synthesis and maintenance of mitochondrial DNA. SLC25A33 also plays a significant role in cellular energy metabolism, linking cytosolic and mitochondrial nucleotide pools. Mutations or dysregulation of this gene can impact mitochondrial function and have been implicated in various metabolic disorders and mitochondrial diseases.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMSC-MCP; Bone marrow stromal cell mitochondrial carrier protein; huBMSC-MCP; mitochondrial carrier protein; novel mitochondrial carrier protein; PNC1 protein; Protein PNC1; solute carrier family 25 (pyrimidine nucleotide carrier), member 33; Solute carrier family 25 member 33; solute carrier family 25, member 33
基因别名: BMSC-MCP; PNC1; SLC25A33
UniProt ID: (Human) Q9BSK2
Entrez Gene ID: (Human) 84275
mitochondrial genome maintenance
regulation of oxidative phosphorylation
mitochondrial DNA replication
transcription from mitochondrial promoter
translation
pyrimidine nucleotide transport
mitochondrion organization
positive regulation of cell proliferation
positive regulation of cell growth
mitochondria-nucleus signaling pathway
cellular response to insulin stimulus
mitochondrial respiratory chain complex III assembly
regulation of mitochondrial membrane potential
regulation of cell cycle arrest
regulation of reactive oxygen species biosynthetic process
cellular response to insulin-like growth factor stimulus
mitochondrial pyrimidine nucleotide import
