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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Arachidonate--CoA ligase; FATP-2; Fatty acid transport protein 2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain fatty acid transport protein 2; Long-chain-fatty-acid--CoA ligase; Phytanate--CoA ligase; Slc27a2; solute carrier family 27 (fatty acid transporter), member 32; Solute carrier family 27 member 2; THCA-CoA ligase; ve; Very long-chain acyl-CoA synthetase; very long-chain acyl-Coenzyme A dehydrogenase synthase; Very long-chain-fatty-acid-CoA ligase; VLACS; VLCS
基因别名: ACSVL1; FACVL1; FATP2; SLC27A2; Vlac; VLACS; VLCS
UniProt ID: (Rat) P97524, (Mouse) O35488
Entrez Gene ID: (Rat) 65192, (Mouse) 26458