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Invitrogen
SLC30A1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-37463
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 200-250 of human ZnT-1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous protein at a molecular weight of 55 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: solute carrier family 30 (zinc transporter), member 1; solute carrier family 30 member 1; unnamed protein product; zinc resistance conferring homolog; zinc transporter 1; znT-1
基因别名: C130040I11Rik; ZNT1; ZRC1
UniProt ID: (Human) Q9Y6M5, (Rat) Q62720, (Mouse) Q60738
Entrez Gene ID: (Human) 7779, (Rat) 58976, (Mouse) 22782
in utero embryonic development
cation transport
copper ion transport
zinc II ion transport
cellular calcium ion homeostasis
cellular zinc ion homeostasis
detoxification of zinc ion
defense response to bacterium
negative regulation of neurotransmitter secretion
transmembrane transport
positive regulation of dendritic spine morphogenesis
zinc ion import into organelle
calcium ion import
cadmium ion transmembrane transport
calcium ion transmembrane transport
zinc II ion transmembrane transport
negative regulation of zinc ion transmembrane import
detoxification of cadmium ion
negative regulation of calcium ion import
zinc export across plasma membrane
regulation of postsynaptic density protein 95 clustering
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
