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Abnova
SLC4A8 Monoclonal Antibody (1G10)
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产品信息
H00009498-M05
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
1G10
抗原
SLC4A8 (NP_004849, 187 a.a. approximately 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: IEEISDLILD QQELSSDLND SMRVKVREAL LKKHHHQNEK KRNNLIPIVR SFAEVGKKQS DPHLMDKHGQ TVSPQSVPTT NLEVKNGVNC EHSPVDLSKV
靶标信息
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Electroneutral Na(+)-driven Cl-HCO3 exchanger; Electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; k-NBC3; slc4a8; sodium bicarbonate cotransporter isoform 3 kNBC-3; Solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
基因别名: AW493845; C230026C11; KIAA0739; kNBC-3; NBC; NBC3; NDCBE; NDCBE1; SLC4A8
UniProt ID: (Human) Q2Y0W8, (Mouse) Q8JZR6
Entrez Gene ID: (Human) 9498, (Mouse) 59033
