Search
Abnova
SLC4A8 Monoclonal Antibody (1G10)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00009498-M05
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
1G10
抗原
SLC4A8 (NP_004849, 187 a.a. approximately 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: IEEISDLILD QQELSSDLND SMRVKVREAL LKKHHHQNEK KRNNLIPIVR SFAEVGKKQS DPHLMDKHGQ TVSPQSVPTT NLEVKNGVNC EHSPVDLSKV
靶标信息
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: electroneutral Na(+)-driven Cl-HCO3 exchanger; electroneutral Na+-driven Cl-HCO3 exchanger; k-NBC3; membrane transporter; NDCBE; NDCBE1; solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8; unnamed protein product
基因别名: C230026C11; kNBC-3; NBC3; NDCBE
UniProt ID: (Human) Q2Y0W8, (Mouse) Q8JZR6
Entrez Gene ID: (Human) 9498, (Mouse) 59033
inorganic anion exchanger activity
zinc ion binding
anion transmembrane transporter activity
sodium:bicarbonate symporter activity
sodium ion transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
identical protein binding
sodium,bicarbonate:chloride antiporter activity
secondary active transmembrane transporter activity
anion transport
bicarbonate transport
sodium ion transmembrane transport
regulation of membrane potential
modulation of synaptic transmission
regulation of intracellular pH
transmembrane transport
basolateral protein secretion
chloride transmembrane transport
regulation of synaptic vesicle exocytosis
positive regulation of synaptic vesicle exocytosis
transport across blood-brain barrier
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
