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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: QGSTHAGGFH NVLEQSTNGS RLHIFDFDVD PLRRH
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Electroneutral sodium monocarboxylate cotransporter; Low-affinity sodium-lactate cotransporter; Sodium-coupled monocarboxylate transporter 2; sodium-iodide related cotransporter; solute carrier family 5 (sodium/glucose cotransporter), member 12; solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12; Solute carrier family 5 member 12
基因别名: SLC5A12; SMCT2
UniProt ID: (Human) Q1EHB4
Entrez Gene ID: (Human) 159963
分子生物学功能: secondary carrier transporter