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Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4F2; 4F2 LC; 4F2 light chain; 4F2HC; 4T2HC; CD98HC; L-type amino acid transporter 1; Large neutral amino acids transporter small subunit 1; LAT1; MDU1; MP hLAT1; NACAE; Solute carrier family 7 member 5
基因别名: 4F2LC; D0H16S474E; LAT1; Slc7a5; TA1
UniProt ID: (Mouse) Q9Z127
Entrez Gene ID: (Mouse) 20539