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Invitrogen
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This target displays homology in the following species: Cow: 86%; Dog: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 93%; Rat: 93%
Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, NHE isoforms 2-6 have distinct tissue- and cell type-dependent expression and inhibitiory characteristics by amiloride analogs. Human NHE-5 transcript (solute carrier family 9, isoform-5, SLC9A5) is an 896 amino acid protein that is expressed in brain, testis, spleen and skeletal muscle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Na(+)/H(+) exchanger 5; NHE-5; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger 5; Solute carrier family 9 member 5
基因别名: Gm696; Nhe5; Slc9a5
UniProt ID: (Mouse) B2RXE2
Entrez Gene ID: (Mouse) 277973