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Invitrogen
SLIT1 Polyclonal Antibody
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SLIT1 Antibody (PA5-95763) in WB
Western blot analysis of SLIT1 in extracts of 293T cells. Samples were incubated with SLIT1 Polyclonal antibody (Product # PA5-95763) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
产品信息
PA5-95763
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_0030522)
偶联物
形式
Liquid
浓度
1.43 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RNLYINNELQ DFTKTQMKPG VVPGCEPCRK LYCLHGICQP NATPGPMCHC EAGWVGLHCD QPADGPCHGH KCVHGQCVPL DALSYSCQCQ DGYSGALCNQ AGALAEPCRG LQCLHGHCQA SGTKGAHCVC DPGFSGELCE QESECRGDPV RDFHQVQRGY AICQTTRPLS WVECRGSCPG QGCCQGLRLK RRKFTFECSD GTSFAEEVEK PTKCGCALCA; Positive Samples: 293T
靶标信息
SLIT1 is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Multiple EGF-like domains protein 4; Multiple epidermal growth factor-like domains protein 4; slit homolog 1; Slit homolog 1 protein; Slit-1
基因别名: KIAA0813; MEGF4; SLIL1; SLIT-1; SLIT1; SLIT3
UniProt ID: (Human) O75093
Entrez Gene ID: (Human) 6585
axon guidance
motor neuron axon guidance
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
retinal ganglion cell axon guidance
dorsal/ventral axon guidance
Roundabout signaling pathway
establishment of nucleus localization
axon extension involved in axon guidance
forebrain morphogenesis
regulation of axonogenesis
negative chemotaxis
negative regulation of synapse assembly
