Invitrogen

SLIT2 Monoclonal Antibody (984724)

查看其他11个SLIT2抗体

问题与答案

问题与答案

问题与答案

Immunogen image

SLIT2 Monoclonal Antibody (984724)

Immunogen Image SLIT2 Monoclonal Antibody (984724)

产品信息

MA5-61558

应用

建议稀释比

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酶联免疫吸附实验 (ELISA)

Assay-dependent

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

984724

抗原

Human embryonic kidney cell line HEK293-derived recombinant human Slit2, Thr1122-Ser1529

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with trehalose

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

SLIT2 are ligands for Robo receptors and play a vital role for axonal migration/navigation during neural development. A number of cleavage products through alternate splicing are reported in the literature for SLIT2 proteins. The C-terminal cleavage proteins are more diffusible than the larger N-terminal protein that is more tightly cell associated. SLIT2 protein is expressed in tissues such as fetal lung, kidney, and adult spinal cord.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Slit homolog 2 protein; Slit-2

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基因别名: SLIL3; Slit-2; SLIT2

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UniProt ID: (Human) O94813

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Entrez Gene ID: (Human) 9353

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GTPase inhibitor activity calcium ion binding protein binding heparin binding identical protein binding protein homodimerization activity laminin-1 binding proteoglycan binding heparan sulfate proteoglycan binding Roundabout binding immunoglobulin superfamily cell adhesion molecule

ureteric bud development negative regulation of protein phosphorylation cell migration involved in sprouting angiogenesis negative regulation of leukocyte chemotaxis axon guidance motor neuron axon guidance negative regulation of lamellipodium assembly negative regulation of endothelial cell migration negative regulation of smooth muscle cell migration spinal cord development chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration chemorepulsion involved in postnatal olfactory bulb interneuron migration corticospinal neuron axon guidance through spinal cord negative regulation of cell growth negative regulation of cell migration negative regulation of actin filament polymerization retinal ganglion cell axon guidance response to nutrient levels cellular response to hormone stimulus negative regulation of GTPase activity Roundabout signaling pathway positive regulation of apoptotic process negative regulation of vascular permeability branching morphogenesis of an epithelial tube axon extension involved in axon guidance negative regulation of inflammatory response positive regulation of axonogenesis negative chemotaxis induction of negative chemotaxis negative regulation of small GTPase mediated signal transduction response to cortisol apoptotic process involved in luteolysis negative regulation of chemokine-mediated signaling pathway cellular response to heparin negative regulation of smooth muscle cell chemotaxis negative regulation of mononuclear cell migration negative regulation of neutrophil chemotaxis negative regulation of monocyte chemotaxis negative regulation of retinal ganglion cell axon guidance negative regulation of cellular response to growth factor stimulus