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Positive Samples: HeLa, LO2
Immunogen sequence: IDTENLREEK DSEITSTRDE LLSARDEILL LHQAAAKVAS ERDTDIASLQ EELKKVRAEL ERWRKAASEY EKEITSLQNS FQLRCQQCED QQREEATRLQ GELEKLRKEW NALETECHSL KRENVLLSSE LQRQEKELHN SQKQSLELTS DLSILQMSRK ELENQVGSLK EQHLRDSADL KTLLSKAENQ AKDVQKEYEK TQTVLSELKL KFEMTEQEKQ SITDELKQCK NNLKLLREKG NNKPWPWMPM L
Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sarcolemmal membrane-associated protein; Sarcolemmal-associated protein
基因别名: D330001L02Rik; KIAA1601; mKIAA1601; SLAP; SLMAP; UNQ1847/PRO3577
UniProt ID: (Human) Q14BN4, (Mouse) Q3URD3
Entrez Gene ID: (Human) 7871, (Mouse) 83997, (Rat) 290533