SMAD2/SMAD3 Polyclonal Antibody

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding phosphatase binding ubiquitin protein ligase binding type I transforming growth factor beta receptor binding identical protein binding SMAD binding tau protein binding RNA polymerase II sequence-specific DNA binding transcription factor binding co-SMAD binding I-SMAD binding R-SMAD binding disordered domain specific binding DNA-binding transcription factor binding transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding transcription corepressor binding transcription coactivator binding collagen binding beta-catenin binding zinc ion binding ligand-dependent nuclear receptor binding DEAD/H-box RNA helicase binding enzyme binding protein kinase binding chromatin DNA binding mineralocorticoid receptor binding sterol response element binding glucocorticoid receptor binding protein homodimerization activity ubiquitin binding bHLH transcription factor binding sequence-specific DNA binding promoter-specific chromatin binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity activating transcription factor binding metal ion binding protein heterodimerization activity transcription factor activity, RNA polymerase II core promoter sequence-specific transcription factor activity, protein binding RNA polymerase II activating transcription factor binding transcription regulatory region DNA binding DNA-binding transcription factor gene-specific transcriptional regulator

ureteric bud development mesoderm formation regionalization determination of left/right asymmetry in lateral mesoderm aortic valve morphogenesis pulmonary valve morphogenesis endocardial cushion morphogenesis transcription, DNA-templated regulation of transcription, DNA-templated transforming growth factor beta receptor signaling pathway zygotic specification of dorsal/ventral axis gastrulation mesoderm development anatomical structure morphogenesis embryonic pattern specification anterior/posterior pattern specification negative regulation of gene expression positive regulation of epithelial to mesenchymal transition regulation of transforming growth factor beta receptor signaling pathway cell differentiation negative regulation of ossification positive regulation of BMP signaling pathway primary miRNA processing activin receptor signaling pathway intracellular signal transduction nodal signaling pathway cell fate commitment negative regulation of cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of multicellular organismal process SMAD protein signal transduction mesenchyme development trophoblast cell migration secondary palate development response to cholesterol odontoblast differentiation negative regulation of transcription from RNA polymerase II promoter MAPK cascade osteoblast differentiation response to hypoxia release of cytochrome c from mitochondria regulation of transcription from RNA polymerase II promoter immune response JNK cascade negative regulation of cell proliferation response to gamma radiation gene expression positive regulation of gene expression signal transduction involved in regulation of gene expression negative regulation of cell growth adrenal gland development positive regulation of cell migration positive regulation of bone mineralization negative regulation of lipopolysaccharide-mediated signaling pathway positive regulation of chondrocyte differentiation developmental process positive regulation of interleukin-1 beta production regulation of transforming growth factor beta2 production positive regulation of transforming growth factor beta3 production negative regulation of osteoblast proliferation cellular response to platelet-derived growth factor stimulus wound healing T cell activation negative regulation of protein catabolic process response to cocaine positive regulation of protein import into nucleus negative regulation of apoptotic process cell-cell junction organization positive regulation of nitric oxide biosynthetic process negative regulation of fat cell differentiation negative regulation of inflammatory response regulation of immune response protein stabilization positive regulation of positive chemotaxis negative regulation of cytosolic calcium ion concentration positive regulation of stress fiber assembly regulation of mitochondrial membrane potential positive regulation of focal adhesion assembly transdifferentiation positive regulation of SMAD protein import into nucleus regulation of dendritic spine morphogenesis negative regulation of wound healing negative regulation of lung blood pressure cellular response to glucose stimulus cellular response to growth factor stimulus cellular response to transforming growth factor beta stimulus negative regulation of transforming growth factor beta production positive regulation of canonical Wnt signaling pathway apoptotic signaling pathway extrinsic apoptotic signaling pathway response to alcohol cellular response to virus transforming growth factor beta receptor superfamily signaling pathway positive regulation of extracellular matrix assembly regulation of miRNA transcription negative regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of pri-miRNA transcription from RNA polymerase II promoter negative regulation of cardiac muscle hypertrophy in response to stress response to angiotensin in utero embryonic development endoderm formation transcription from RNA polymerase II promoter protein phosphorylation common-partner SMAD protein phosphorylation SMAD protein complex assembly pattern specification process endoderm development heart development response to glucose post-embryonic development insulin secretion lung development pancreas development organ growth developmental growth embryonic foregut morphogenesis embryonic cranial skeleton morphogenesis regulation of binding palate development pericardium development positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry skeletal system development somitogenesis liver development negative regulation of protein phosphorylation heart looping osteoblast development immune system development transport activation of cysteine-type endopeptidase activity involved in apoptotic process cell cycle arrest positive regulation of alkaline phosphatase activity regulation of striated muscle tissue development evasion or tolerance of host defenses by virus thyroid gland development positive regulation of catenin import into nucleus positive regulation of transcription factor import into nucleus negative regulation of osteoblast differentiation negative regulation of mitotic cell cycle regulation of epithelial cell proliferation lens fiber cell differentiation activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway