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SMC3 Antibody (PA5-119438) in IHC (P)
Immunohistochemistry analysis of SMC3 in paraffin-embedded Human Stomach cancer tissue. Samples were incubated with polyclonal antibody (Product # PA5-119438) at a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
产品信息
PA5-119438
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Structural Maintenance Of Chromosomes Protein 3. The antigen corresponds to amino acid range 994-1181 of the target protein.
偶联物
形式
Liquid
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903936
靶标信息
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bamacan; Basement membrane-associated chondroitin proteoglycan; Chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); Chromosome-associated polypeptide; hCAP; SMC protein 3; Structural maintenance of chromosomes protein 3
基因别名: BAM; BMH; CDLS3; CSPG6; HCAP; SMC3; SMC3L1
UniProt ID: (Human) Q9UQE7
Entrez Gene ID: (Human) 9126
regulation of DNA replication
DNA repair
mitotic spindle organization
sister chromatid cohesion
mitotic sister chromatid cohesion
mitotic nuclear division
meiotic nuclear division
signal transduction
protein sumoylation
stem cell population maintenance
negative regulation of DNA endoreduplication
cell division
