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Invitrogen
SMG6 Polyclonal Antibody
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图: 1 / 3
SMG6 Antibody (PA5-115202) in ICC/IF
Immunocytochemistry analysis of SMG6 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115202). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115202
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SMG6(Accession Q86US8), corresponding to amino acid residues P24-F74.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total EST1A.
靶标信息
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EST1-like protein A; Ever shorter telomeres 1A; hEST1A; hSmg5/7a; Nonsense mediated mRNA decay factor SMG6; Smg-6 homolog; Smg-6 homolog, nonsense mediated mRNA decay factor; telomerase subunit EST1A; Telomerase-binding protein EST1A
基因别名: AI317223; AU041178; C17orf31; EST1A; KIAA0732; LRRGT00040; RGD1309609; SMG6
UniProt ID: (Mouse) P61406
Entrez Gene ID: (Mouse) 103677, (Rat) 287522
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