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Invitrogen
SMU1 Polyclonal Antibody
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产品信息
PA5-54062
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.40 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SIEIESSDVI RLIMQYLKEN SLHRALATLQ EETTVSLNTV DSIESFVADI NSGHWDTVLQ AIQSLKLPDK TLIDLYEQVV LELIELRELG AARSLLRQTD PMIML
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; functional spliceosome-associated protein 57; homolog of C. elegans smu-1; smu-1 suppressor of mec-8 and unc-52 homolog; Smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; WD40 repeat-containing protein SMU1
基因别名: 2600001O03Rik; 2610203K23Rik; AB044414; AI845086; AW556129; BWD; fSAP57; SMU-1; SMU1
UniProt ID: (Human) Q2TAY7, (Mouse) Q3UKJ7, (Rat) Q99M63
Entrez Gene ID: (Human) 55234, (Mouse) 74255, (Rat) 117541
