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Invitrogen
SNRPB Polyclonal Antibody
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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SNRPB Antibody (PA5-84769)
Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. Caco-2 were transfected with, control siRNA, SNRPB siRNA (probe #1), and SNRPB siRNA (probe #2) and a decrease in signal intensity was observed in Western Blot application using anti-SNRPB Polyclonal Antibody (Product # PA5-84769) used at a dilution of 0.4 µg/mL. Anti-GAPDH was used as a loading control. {KD}
产品信息
PA5-84769
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Anitgen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2791919
产品详细信息
Immunogen sequence: QAPAGLAGPV RGVGGPSQQV MTPQGRGT
靶标信息
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B polypeptide of Sm protein; Sm protein B/B'; Sm-B/B'; sm-B/Sm-B'; small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein-associated proteins B and B'; snRNP-B
基因别名: CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB; SNRPB1
UniProt ID: (Human) P14678
Entrez Gene ID: (Human) 6628
spliceosomal snRNP assembly
mRNA splicing, via spliceosome
positive regulation of defense response to virus by host
termination of RNA polymerase II transcription
protein methylation
histone mRNA metabolic process
RNA splicing
nuclear import
mitophagy in response to mitochondrial depolarization
xenophagy
