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Invitrogen
SNX1 Recombinant Rabbit Monoclonal Antibody (24GB2595)
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SNX1 Antibody (MA5-57732) in ICC/IF
Immunocytochemical staining of SNX1 in HepG2 cells using SNX1 Recombinant Monoclonal Antibody (Product # MA5-57732) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; Sorting nexin 1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-57732
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB2595
抗原
A synthesized peptide derived from human SNX1 (aa 50-100)
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC8664; SNX1A; sorting nexin 1A; Sorting nexin-1
基因别名: HsT17379; SNX1; VPS5
UniProt ID: (Human) Q13596, (Rat) Q99N27
Entrez Gene ID: (Human) 6642, (Rat) 84471
epidermal growth factor receptor binding
insulin receptor binding
protein binding
phosphatidylinositol binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
cadherin binding involved in cell-cell adhesion
transferrin receptor binding
leptin receptor binding
scaffold/adaptor protein
