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Bethyl Laboratories
SNX15 Polyclonal Antibody
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SNX15 Antibody (A305-639A-T) in IP
Detection of human SNX15 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SNX15 antibody A305-639A-M (lot A305-639A-M-1) used for IP at 8 µl per reaction. SNX15 was also immunoprecipitated by rabbit anti-SNX15 antibody BL22458. For blotting immunoprecipitated SNX15, A305-639A-M was used at 1:1000. Detection: Chemiluminescence with an exposure time of 3 min... View More
产品信息
A305-639A-T
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A region between residue 225 to 275 of human Sorting nexin-15.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: clone iota unknown protein; hCG_23393; OTTHUMP00000035515; Sorting nexin-15
基因别名: HSAF001435; SNX15
UniProt ID: (Human) Q9NRS6
Entrez Gene ID: (Human) 29907
