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Invitrogen
SNX9 Polyclonal Antibody
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SNX9 Antibody (PA5-18485) in ICC/IF
Immunocytochemistry analysis of SNX9 using SNX9 Polyclonal Antibody (Product # PA5-18485) in paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-18485
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (HKGAIEKVKESDK) corresponding to the internal amino acids of SNX9 (aa 510-523).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with canine and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MST155; MSTP155; OTTHUMP00000040083; putative ATP/GTP binding protein; RP11-266C7.10; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; unnamed protein product; Wiskott-Aldrich syndrome protein (WASP) interactor protein
基因别名: SDP1; SH3PX1; SH3PXD3A; WISP
UniProt ID: (Human) Q9Y5X1
Entrez Gene ID: (Human) 51429
mitotic cell cycle
mitotic cytokinesis
intracellular protein transport
endocytosis
receptor-mediated endocytosis
positive regulation of catabolic process
protein transport
endosomal transport
positive regulation of actin filament polymerization
cleavage furrow formation
positive regulation of GTPase activity
positive regulation of protein kinase activity
positive regulation of membrane protein ectodomain proteolysis
lipid tube assembly
protein-containing complex assembly
membrane tubulation
regulation of synaptic vesicle endocytosis
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