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Invitrogen
SNX9 Polyclonal Antibody
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SNX9 Antibody (PA5-87542) in WB
Western blot analysis of SNX9 in extracts of various cell lines. Samples were incubated with SNX9 Polyclonal antibody (Product # PA5-87542) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-87542
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SNX9 (NP_0573081)
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MATKARVMYD FAAEPGNNEL TVNEGEIITI TNPDVGGGWL EGRNIKGERG LVPTDYVEIL PSDGKDQFSC GNSVADQAFL DSLSASTAQA SSSAASNNHQ VGSGNDPWSA WSASKSGNWE SSEGWGAQPE GAGAQRNTNT PNNWDTAFGH PQAYQGPATG DDDDWDEDWD GPKSSSYFKD SESADAGGAQ RGNSRASSSS MKIPLNKFPG; Positive Samples: A375, HeLa, Mouse liver, Rat liver, Rat heart; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Cytoplasmic vesicle membrane, Golgi apparatus, Peripheral membrane protein, clathrin-coated vesicle, ruffle, trans-Golgi network
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MST155; MSTP155; OTTHUMP00000040083; Protein SDP1; RP11-266C7.10; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Sorting nexin-9; Wiskott-Aldrich syndrome protein (WASP) interactor protein
基因别名: 2700073N08Rik; SDP1; SH3PX1; SH3PXD3A; SNX9; WISP
UniProt ID: (Human) Q9Y5X1, (Mouse) Q91VH2
Entrez Gene ID: (Human) 51429, (Mouse) 66616, (Rat) 683687
mitotic cytokinesis
intracellular protein transport
endocytosis
receptor-mediated endocytosis
mitotic nuclear division
vesicle organization
endosomal transport
positive regulation of protein oligomerization
cleavage furrow formation
positive regulation of GTPase activity
positive regulation of protein kinase activity
positive regulation of membrane protein ectodomain proteolysis
lipid tube assembly
membrane tubulation
cell-cell adhesion
transport
cell cycle
protein transport
cell division
