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Invitrogen
SOX18 Recombinant Rabbit Monoclonal Antibody (K01_3S12)
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产品信息
MA566914
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_3S12
抗原
A synthesized peptide derived from human SOX18.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol, 150mM NaCl, 0.05% BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SOX18; SRY (sex determining region Y)-box 18; SRY-box 18; Transcription factor SOX-18
基因别名: HLTRS; HLTS; SOX18
UniProt ID: (Human) P35713
Entrez Gene ID: (Human) 54345
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
blood vessel development
vasculogenesis
in utero embryonic development
hair follicle development
vasculature development
lymph vessel development
lymphangiogenesis
heart looping
outflow tract morphogenesis
regulation of transcription, DNA-templated
heart development
tissue development
hair cycle process
embryonic heart tube development
blood vessel endothelial cell migration
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
anatomical structure formation involved in morphogenesis
stem cell fate specification
endocardium formation
lymphatic endothelial cell differentiation
endocardial cell differentiation
establishment of endothelial barrier
regulation of stem cell proliferation
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