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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SOX8 Antibodies

          Invitrogen

          SOX8 Polyclonal Antibody

          查看其他8个SOX8抗体

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          说明书
          实验方案
          问题与答案
          技术支持
          说明书
          实验方案
          问题与答案
          技术支持

          Cite SOX8 Polyclonal Antibody

          • 抗体检测数据 (4)
          SOX8 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          SOX8 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 4

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          SOX8 Antibody (PA5-78487) in ICC/IF

          SOX8 Polyclonal Antibody detects SOX8 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SOX8 protein stained by SOX8 Polyclonal Antibody (Product # PA5-78487) diluted at 1:500. Red: Phalloidin, a cytoskeleton marker, diluted at 1:200. Scale bar = 10 µm. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          SOX8 Antibody in Immunocytochemistry (ICC/IF)
          SOX8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SOX8 Antibody in Western Blot (WB)
          SOX8 Antibody in Western Blot (WB)

          产品信息

          PA5-78487

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:3,000
          -

          免疫组化(石蜡) (IHC (P))

          1:100-1:1,000
          -

          免疫细胞化学 (ICC/IF)

          1:100-1:1,000
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Recombinant protein encompassing a sequence within the center region of human SOX8. The exact sequence is proprietary.

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1.51 mg/mL

          纯化类型

          Antigen affinity chromatography

          保存液

          PBS, pH 7, with 20% glycerol

          内含物

          0.025% ProClin 300

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2736649

          产品详细信息

          Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, human brain

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          靶标信息

          Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

          您是否在文献中引用过该产品?请点击下方按钮邮件告知我们。
          引用该产品

          生物信息学

          蛋白别名: SRY (sex determining region Y)-box 8; SRY box 8; Transcription factor SOX-8

          查看更多 收起

          基因别名: SOX8

          查看更多 收起

          UniProt ID: (Human) P57073

          查看更多 收起

          Entrez Gene ID: (Human) 30812

          查看更多 收起

          功能
          RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding transcription factor binding protein heterodimerization activity
          参与通路
          osteoblast differentiation in utero embryonic development neural crest cell migration transcription, DNA-templated signal transduction spermatogenesis peripheral nervous system development male gonad development regulation of hormone levels positive regulation of gliogenesis positive regulation of osteoblast proliferation skeletal muscle cell differentiation negative regulation of apoptotic process cell fate commitment fat cell differentiation negative regulation of myoblast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter negative regulation of photoreceptor cell differentiation cell maturation enteric nervous system development oligodendrocyte differentiation Sertoli cell development astrocyte fate commitment retina development in camera-type eye retinal rod cell differentiation adipose tissue development morphogenesis of a branching epithelium renal vesicle induction ureter morphogenesis metanephric nephron tubule formation positive regulation of kidney development positive regulation of branching involved in ureteric bud morphogenesis
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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