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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SOX8/9/17/18.
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: mSox9; ragged; SOX9; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY-box 9; SRY-box containing gene 17; SRY-box containing gene 18; SRY-box containing gene 8; SRY-box containing gene 9; Sry-related HMG-box gene 18; SRY-related HMG-box, gene 9; Transcription factor SOX-17; Transcription factor SOX-18; Transcription factor SOX-8; Transcription factor SOX-9; unnamed protein product
基因别名: 2010306G03Rik; AI385749; AV220920; CMD1; CMPD1; ENH13; mKIAA4243; Ra; Ragl; Sox-17; Sox-18; Sox-8; Sox-9; Sox17; Sox18; Sox8; SOX9; SRA1; SRXX2; SRXY10; TESCO
UniProt ID: (Mouse) Q61473, (Mouse) P43680, (Mouse) Q04886, (Rat) F1LYL9, (Mouse) Q04887
Entrez Gene ID: (Human) 6662, (Mouse) 20671, (Rat) 312936, (Rat) 311723, (Mouse) 20672, (Mouse) 20681, (Rat) 302993, (Rat) 140586, (Mouse) 20682