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Invitrogen
SP7 Polyclonal Antibody
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图: 1 / 19
SP7 Antibody (PA5-115697) in IHC (P)
Immunohistochemistry analysis of SP7 in human normal tissues adjacent to colorectal cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115697) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115697
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SP7(Accession Q8TDD2), corresponding to amino acid residues T397-I431.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total osterix.
靶标信息
SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone cell differentiation (Gao et al., 2004 [PubMed 15474293]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C2H2 zinc finger transcription factor; OSX; MGC126598; osteoblast transcription factor; osterix; transcription factor; transcription factor containing 3 Cys2His2-type zinc fingers; Sp7; unnamed protein product; zinc finger protein; zinc finger protein osterix
基因别名: 6430578P22Rik; C22; OI11; OI12; osterix; OSX
UniProt ID: (Human) Q8TDD2, (Mouse) Q8VI67
Entrez Gene ID: (Human) 121340, (Rat) 300260, (Mouse) 170574
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
DEAD/H-box RNA helicase binding
osteoblast differentiation
regulation of transcription from RNA polymerase II promoter
response to mechanical stimulus
gene expression
response to insulin
cellular response to zinc ion starvation
positive regulation of transcription from RNA polymerase II promoter
regulation of hydrolase activity
hematopoietic stem cell differentiation
diphosphate metabolic process
cellular response to parathyroid hormone stimulus
cementum mineralization
positive regulation of stem cell differentiation
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