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Invitrogen
SPG7 Monoclonal Antibody (OTI1C12)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-25907
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI1C12
抗原
Human recombinant protein fragment corresponding to amino acids 300-573 of SPG7 produced in E.coli
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.86 mg/mL
规格
86 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell matrix adhesion regulator; mitochondrial metalloprotease; paraplegin; spastic paraplegia 7 (pure and complicated autosomal recessive); spastic paraplegia 7 homolog; spastic paraplegia 7 protein; SPG7, paraplegin matrix AAA peptidase subunit; unnamed protein product
基因别名: CAR; CMAR; PGN; SPG5C
UniProt ID: (Human) Q9UQ90, (Mouse) Q3ULF4
Entrez Gene ID: (Human) 6687, (Mouse) 234847
proteolysis
mitochondrion organization
nervous system development
mitochondrial protein processing
regulation of mitochondrial membrane permeability
regulation of calcium import into the mitochondrion
mitochondrial outer membrane permeabilization involved in programmed cell death
cell adhesion
anterograde axonal transport
regulation of cell adhesion
calcium ion transmembrane import into mitochondrion
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