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Invitrogen
SPIDR Polyclonal Antibody
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产品信息
PA5-55541
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ENSAKKKLLR GGLAERLNGL QNRERSAISL WRHQCISYQK TLSGRKSGVL TVKILELHEE CAMQVAMCEQ LLGSPATSSS QSVAPR
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
靶标信息
Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA repair-scaffolding protein; k0146; Scaffolding protein involved in DNA repair
基因别名: KIAA0146; SPIDR
UniProt ID: (Human) Q14159
Entrez Gene ID: (Human) 23514
double-strand break repair via homologous recombination
cellular response to DNA damage stimulus
regulation of double-strand break repair via homologous recombination
positive regulation of protein complex assembly
regulation of establishment of protein localization to chromosome
cellular response to ionizing radiation
cellular response to hydroxyurea
cellular response to camptothecin
positive regulation of double-strand break repair
