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Abnova
SPINT2 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010653-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SPINT2 (AAH11951, 1 a.a. approximately 252 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQLCGLRRS RAFLALLGSL LLSGVLAADR ERSIHDFCLV SKVVGRCRAS MPRWWYNVTD GSCQLFVYGG CDGNSNNYLT KEECLKKCAT VTENATGDLA TSRNAADSSV PSAPRRQDPE DHSSDMFNYE EYCTANAVTG PCRASFPRWY FDVERNSCNN FIYGGCRGNK NSYRSEEACM LRCFRQQENP PLPLGSKVVL LAGLFVMVSI LFLGASMVYL IRVARRNQER ALRTVWSSGD DKEQLVKNTY VL
靶标信息
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ45571; HAI-2; Hepatocyte growth factor activator inhibitor type 2; hepatocyte growth factor activator inhibitor-2; HGF activator inhibitor 2; KOP; Kunitz domain containing protein overexpressed in pancreatic cancer; Kunitz-type protease inhibitor 2; Placental bikunin; serine protease inhibitor, Kunitz type, 2; SPINT2; testicular tissue protein Li 183; unnamed protein product
基因别名: DIAR3; HAI-2; HAI2; KOP; PB; SPINT2
UniProt ID: (Human) O43291
Entrez Gene ID: (Human) 10653
neural tube closure
establishment or maintenance of cell polarity
negative regulation of cell-cell adhesion
epithelial cell morphogenesis involved in placental branching
basement membrane organization
cellular response to BMP stimulus
negative regulation of cell motility
negative regulation of neural precursor cell proliferation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
