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Abnova
SPRED2 Monoclonal Antibody (6G8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00200734-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
6G8
抗原
SPRED2 (NP_861449, 120 a.a. approximately 219 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: EDLIEGSTTS SSTIHNEAEL GDDDVFTTAT DSSSNSSQKR EQPTRTISSP TSCEHRRIYT LGHLHDSYPT DHYHLDQPMP RPCRQVSFPD DDEEIVRINP
靶标信息
SPRED2 is a member of the Sprouty /SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (Nonami et al., 2004 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EVH1/Sprouty domain containing protein; sprouty protein with EVH-1 domain 2, related sequence; unnamed protein product
基因别名: NS14; Spred-2
UniProt ID: (Human) Q7Z698
Entrez Gene ID: (Human) 200734
regulation of signal transduction
negative regulation of epithelial to mesenchymal transition
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of MAPK cascade
positive regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of ERK1 and ERK2 cascade
negative regulation of intracellular signal transduction
negative regulation of lens fiber cell differentiation
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