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Invitrogen
SPTAN1 Recombinant Rabbit Monoclonal Antibody (K01_1U61)
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产品信息
MA563414
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_1U61
抗原
A synthetic peptide of human NEAS.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 150mM NaCl, 40% glycerol, 0.05% BSA
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (ALPHA)II-SPECTRIN; a--fodrin; alpha; alpha II spectrin; alpha-fodrin; Alpha-II spectrin; alpha-spectrin 2; alpha-spectrin 2, brain; brain; brain alpha-spectrin; FLJ44613; Fodrin alpha chain; inhibitory protein factor; noerythroid alpha-spectrin 2; Non erythrocytic spectrin alpha; non-erythrocytic 1 (alpha-fodrin); non-erythroid alpha chain; nonerythroid alpha-spectrin 2; Spectrin; Spectrin alpha; Spectrin alpha chain brain; spectrin alpha chain, brain; Spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; Spectrin, non-erythroid alpha subunit
基因别名: 2610027H02Rik; A2a; EIEE5; IPF; NEAS; Spna-2; Spna2; SPTA2; SPTAN1
UniProt ID: (Human) Q13813, (Rat) P16086
Entrez Gene ID: (Human) 6709, (Mouse) 20740, (Rat) 64159
actin binding
Ras guanyl-nucleotide exchange factor activity
structural constituent of cytoskeleton
calcium ion binding
protein binding
calmodulin binding
syntaxin binding
protein complex binding
protein N-terminus binding
cadherin binding involved in cell-cell adhesion
spectrin binding
metal ion binding
protein heterodimerization activity
