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Invitrogen
SRP54 Polyclonal Antibody
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SRP54 Antibody (PA5-104335) in ICC/IF
Immunofluorescent analysis of SRP54 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and SRP54 polyclonal antibody (Product # PA5-104335) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-104335
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SRP54(Accession P61011), corresponding to amino acid residues V470-M504.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SRP54.
靶标信息
Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 54K subunit of signal recognition particle; Signal recognition particle 54 kDa protein; signal recognition particle 54kD; signal recognition particle 54kDa; Signal recognition particle subunit SRP54
基因别名: 54kDa; SRP54
UniProt ID: (Human) P61011, (Mouse) P14576, (Rat) Q6AYB5
Entrez Gene ID: (Human) 6729, (Mouse) 24067, (Rat) 116650
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane, translocation
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
response to drug
protein targeting to ER
biological_process
metabolic process
