Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
SS18 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
SS18 Antibody (PA5-36199) in IHC (P)
Immunohistochemistry analysis of SS18 in paraffin-embedded human colon carcinoma tissue (cytoplasmic and nucleus staining) and negative control (right, with PBS only). Samples were incubated with SS18 polyclonal antibody (Product # PA5-36199) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
产品信息
PA5-36199
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the N-terminal of human SYT
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous protein at a molecular weight of 45 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: MGC116875; Protein SSXT; Protein SYT; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; Synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; Synovial sarcoma-associated Ss18-alpha
基因别名: D130059H17; SS18; SSXT; SYT
UniProt ID: (Human) Q15532, (Mouse) Q62280
Entrez Gene ID: (Human) 6760, (Mouse) 268996, (Rat) 361295
microtubule cytoskeleton organization
cell morphogenesis
transcription, DNA-templated
intracellular signal transduction
response to drug
positive regulation of transcription from RNA polymerase II promoter
ephrin receptor signaling pathway
neuronal stem cell population maintenance
regulation of transcription, DNA-templated
cytoskeleton organization
biological_process
