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Immunogen sequence: TTWFPKQMVL ELSENLKRLI KHRPCTCTHC IGQRKLSAWF DERFNQTMQP LLTAQNALLE DDTYRWWLRL QREKKPNNLN DTIKELFRVV PGNVDPMLEK R; Positive Samples: Mouse liver; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein
ST3GAL1 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. It is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of ST3GAL1 protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B.The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase; Gal beta1,3 GalNAc alpha2,3 sialyltransferase; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; Gal-NAc6S; MGC9183; Monosialoganglioside sialyltransferase; Sialyltransferase 4A; sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); SIAT4-A; ST3Gal I; ST3GAL-I sialyltransferase; ST3GalA.1; ST3GalI; ST3O
基因别名: 5330418N22Rik; AI467004; Siat4; Siat4a; St3gal-1; St3gal1; ST3GalI
UniProt ID: (Mouse) P54751
Entrez Gene ID: (Mouse) 20442
分子生物学功能: transferase