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Invitrogen
ST5 Polyclonal Antibody
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产品信息
PA5-61331
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PSSPTENGTE NQPKFGSKST LEENAYEDIV GDLPKENPYE DVDLKSRRAG RKSQQLSENS LDSLHRMWSP QDRKYNSPPT QLSLKPNSQS LRSGNWSERK
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 65%.
靶标信息
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DENN domain-containing protein 2B; DENN/MADD domain containing 2B; HeLa tumor suppression 1; p70; Suppression of tumorigenicity 5 protein
基因别名: DENND2B; HTS1; p126; ST5
UniProt ID: (Human) P78524
Entrez Gene ID: (Human) 6764
