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Invitrogen
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Immunogen sequence: YRLPNEKEIV QGVLQQGTAW RRNQTAARAF RKQMEDCCDP AHLFAMTKMN SPMGKSMWYD GEFLYSFTID NSTYSLFPQA TPFQLPLKKC AVVGNGGILK KSGCGRQIDE ANFVMRCNLP PLSSEYTKDV GSKSQLVTAN PSIIRQRFQN LLWSRKTFVD NMKIYNHSYI YMPAFSMKTG TEPSLRVYYT LSDVGANQTV LFANPNFLRS IGKFWKSRGI HA; Positive Samples: A-549, SGC-7901; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha-2, 8-sialyltransferase; Alpha-2,8-sialyltransferase 8A; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Ganglioside GD3 synthase; Ganglioside GT3 synthase; GD3 synthase; sialyltransferase 8 A; Sialyltransferase 8A; Sialyltransferase St8Sia I; sialytransferase St8Sia I; SIAT8-A; ST8Sia I; ST8SiaI
基因别名: 9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a; St8sia1
UniProt ID: (Mouse) Q64687
Entrez Gene ID: (Mouse) 20449