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Invitrogen
STAG2 Recombinant Rabbit Monoclonal Antibody (1H3L8)
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STAG2 Antibody (702499) in ICC/IF
Knockdown of STAG2 was achieved by transfecting HeLa cells with STAG2 specific siRNA (Silencer® select Product # s21089). Immunofluorescence analysis was performed on HeLa cells (untransfected, panel a-d), and cells transfected with STAG2 specific siRNA (panel i-l) or non-specific scrambled siRNA (panels e-h). Cells were fixed, permeabilized, and labelled with Anti-STAG2 Recombinant Rabbit Monoclonal Antibody (Product # 702499, 2 µg/mL), followed by Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjug... View More
产品信息
702499
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1H3L8
抗原
Peptides corresponding to human [1) aa1213-aa1231, 2) aa438-aa457]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Monkey, Dog, Sheep
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
STAG2 is a component of the cohesin complex. This complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cohesin subunit SA-2; DKFZp686P168; DKFZp781H1753; FLJ25871; OTTHUMP00000024338; OTTHUMP00000043514; OTTHUMP00000043515; OTTHUMP00000081754; OTTHUMP00000081755; RP11-517O1.1; SCC3 homolog 2; Stromal antigen 2
基因别名: bA517O1.1; SA-2; SA2; SCC3B; STAG2
UniProt ID: (Human) Q8N3U4
Entrez Gene ID: (Human) 10735
