Osenses

STAM 1, 2 Polyclonal Antibody

Name: STAM 1, 2 Polyclonal Antibody
Brand: Osenses
SKU: OSS00106G-500UG

1 篇参考文献

查看其他2个STAM1/STAM2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

OSS00106G-500UG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

10-50 µg/mL

免疫组化 (IHC)

10-50 µg/mL

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Non-human primate, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from human STAM 1, 2 (STAM-1, STAM-2) conjugated to blue carrier protein was used as the antigen

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

纯化类型

Ammonium sulfate precipitation

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in many species including rat, mouse, zebra fish and xenopus.

Specificity of this antibody: STAM1 and 2.

靶标信息

STAM1 is involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and c-myc induction. May also play a role in endocytic trafficking as well as in T-cell development. Subunit: Heterodimer. Composed of STAM1 and HGS/HRS. Also interacts directly with STAMBP/AMSH. Tissue Specificity: Ubiquitously expressed. STAM2 is involved in intracellular signal transduction mediated by cytokines and growth factors. Probably acts via its association with ubiquitinated cargo proteins on the early endosome participates in their sorting for trafficking to the lysosome. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and c-myc induction. May also play a in T-cell development. Subunit: Heterodimer or heterotrimer. At least composed of STAM2 and HGS/Hrs. EPS15 can be part of the complex. Interacts directly with STAMBP/AMSH, JAK2 and JAK3. Also interacts with ubiquitinated proteins and the deubiquitinating enzyme USP8/UBPY. Interacts directly with CBX5 via the PxVxL motif. Interacts with VPS37C. Tissue Specificity: Ubiquitously expressed.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: Hrs binding protein; Hrs-binding protein; HSE1 homolog; Signal transducing adapter molecule 1; Signal transducing adapter molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; STAM-1; STAM-2; STAM-like protein containing SH3 and ITAM domains 2

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基因别名: 1200004O12Rik; 5730456G07Rik; BB145015; HBP; RGD1564499; STAM; STAM-1; STAM1; STAM2; STAM2A; STAM2B