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Invitrogen
STAMBP Polyclonal Antibody
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产品信息
PA5-115965
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human STAMBP(Accession O95630), corresponding to amino acid residues S368-V418.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total STAMBP.
靶标信息
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase; MGC126516; MGC126518; STAM-binding protein; testicular secretory protein Li 54
基因别名: 5330424L14Rik; 5730422L11Rik; AMSH; AW107289; MICCAP; mKIAA4198; STAMBP
UniProt ID: (Human) O95630, (Rat) Q8R424, (Mouse) Q9CQ26
Entrez Gene ID: (Human) 10617, (Rat) 171565, (Mouse) 70527
mitotic cytokinesis
JAK-STAT cascade
positive regulation of cell proliferation
negative regulation of phosphatidylinositol 3-kinase signaling
protein deubiquitination
negative regulation of neuron apoptotic process
negative regulation of Ras protein signal transduction
proteolysis
biological_process
