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Invitrogen
STAMBP Polyclonal Antibody
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产品信息
PA5-77119
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human STAMBP.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase; MGC126516; MGC126518; STAM-binding protein; testicular secretory protein Li 54
基因别名: 5330424L14Rik; 5730422L11Rik; AMSH; AW107289; MICCAP; mKIAA4198; STAMBP
UniProt ID: (Human) O95630, (Rat) Q8R424, (Mouse) Q9CQ26
Entrez Gene ID: (Human) 10617, (Rat) 171565, (Mouse) 70527
protein binding
peptidase activity
metallopeptidase activity
hydrolase activity
protein domain specific binding
metal ion binding
Lys63-specific deubiquitinase activity
ubiquitinyl hydrolase activity
metal-dependent deubiquitinase activity
molecular_function
thiol-dependent ubiquitin-specific protease activity
pyroglutamyl-peptidase activity
metalloprotease
mitotic cytokinesis
proteolysis
JAK-STAT cascade
positive regulation of cell proliferation
protein deubiquitination
negative regulation of Ras protein signal transduction
negative regulation of protein kinase B signaling
protein K63-linked deubiquitination
hippocampal neuron apoptotic process
negative regulation of hippocampal neuron apoptotic process
biological_process
negative regulation of phosphatidylinositol 3-kinase signaling
negative regulation of neuron apoptotic process
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