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Invitrogen
STARD13 Polyclonal Antibody
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图: 1 / 6
STARD13 Antibody (PA5-99309) in ICC/IF
Immunofluorescent analysis of STARD13 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and STARD13 polyclonal antibody (Product # PA5-99309) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99309
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human STARD13(Accession Q9Y3M8), corresponding to amino acid residues L106-V156.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total STA13.
靶标信息
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deleted in liver cancer 2 protein; long intergenic non-protein coding RNA 464; Rho GTPase activating protein on chromosome 13q12; RhoGAP; RhoGAP; DLC2gamma; SAM domain protein; DLC2delta; serologically defined colon cancer antigen 13; serologically defined colon cancer antigen 28; STA13; StAR-related lipid transfer (START) domain containing 13; START domain-containing protein 13; unnamed protein product
基因别名: ARHGAP37; DLC2; GT650; LINC00464
UniProt ID: (Human) Q9Y3M8, (Mouse) Q923Q2
Entrez Gene ID: (Human) 90627, (Mouse) 243362
signal transduction
actin cytoskeleton organization
regulation of Rho protein signal transduction
endothelial cell migration
negative regulation of cell migration involved in sprouting angiogenesis
endothelial tube lumen extension
negative regulation of sprouting angiogenesis
negative regulation of cell migration
regulation of small GTPase mediated signal transduction
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