Abnova

STIM1 Monoclonal Antibody (6C6)

Name: STIM1 Monoclonal Antibody (6C6)
Brand: Abnova
SKU: H00006786-M02

查看其他27个STIM1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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STIM1 Antibody (H00006786-M02) in ELISA

Detection limit for recombinant GST tagged STIM1 is 0.3 ng/mL as a capture antibody.

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产品信息

H00006786-M02

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

6C6

抗原

STIM1 (AAH21300, 24 a.a. approximately 685 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.32 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Sandwich ELISA (Recombinant protein).

Immunogen sequence: SHSHSEKATG TSSGANSEES TAAEFCRIDK PLCHSEDEKL SFEAVRNIHK LMDDDANGDV DVEESDEFLR EDLNYHDPTV KHSTFHGEDK LISVEDLWKA WKSSEVYNWT VDEVVQWLIT YVELPQYEET FRKLQLSGHA MPRLAVTNTT MTGAVLKMTD RSHRQKLQLK ALDTVLFGPP LLTRHNHLKD FMLVVSIVIG VGGCWFAYIQ NRYSKEHMKK MMKDLEGLHR AEQSLHDLQE RLHKAQEEHR TVEVEKVHLE KKLRDEINLA KQEAQRLKEL REGTENERSR QKYAEEELEQ VREALRKAEK ELESHSSWYA PEALQKWLQL THEVEVQYYN IKKQNAEKQL LVAKEGAEKI KKKRNTLFGT FHVAHSSSLD DVDHKILTAK QALSEVTAAL RERLHRWQQI EILCGFQIVN NPGIHSLVAA LNIDPSWMGS TRPNPAHFIM TDDVDDMDEE IVSPLSMQSP SLQSSVRQRL TEPQHGLGSQ RDLTHSDSES SLHMSDRQRV APKPPQMSRA ADEALNAMTS NGSHRLIEGV HPGSLVEKLP DSPALAKKAL LALNHGLDKA HSLMELSPSA PPGGSPHLDS SRSHSPSSPD PDTPSPVGDS RALQASRNTR IPHLAGKKAV AEEDNGSIGE ETDSSPGRKK FPLKIFKKPL KK

靶标信息

STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.

仅用于科研。不用于诊断过程。未经明确授权不得转售。