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Invitrogen
STMN3 Polyclonal Antibody
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STMN3 Antibody (PA5-101914) in ICC/IF
Immunocytochemistry analysis of STMN3 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with STMN3 polyclonal antibody (Product # PA5-101914) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-101914
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human STMN3(Accession Q9NZ72), corresponding to amino acid residues M40-E90.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total STMN3.
靶标信息
This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hippocampus abundant transcript 3; SCG10-like protein; SCG10-like-protein; SCG10-related protein HiAT3; Scgn10 like-protein; Stathmin-3; stathmin-like 3
基因别名: 9330161A03Rik; AI604839; R75323; SCLIP; STMN3
UniProt ID: (Human) Q9NZ72, (Mouse) O70166
Entrez Gene ID: (Human) 50861, (Mouse) 20262, (Rat) 29246
microtubule depolymerization
nervous system development
regulation of microtubule polymerization or depolymerization
cytoplasmic microtubule organization
neuron projection development
negative regulation of Rac protein signal transduction
regulation of GTPase activity
regulation of cytoskeleton organization
