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Invitrogen
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Immunogen sequence: PGLLLCEPTE LYNILNQATK LSRLTDPNYL CLLDVRSKWE YDESHVITAL RVKKKNNEYL LPESVDLECV KYCVVYDNNS STLEILLKDD DDDSDSDGDG KD
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 63%.
Catalytically inactive phosphatase (PubMed:20180778, PubMed:23163895). By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules (PubMed:20180778, PubMed:23163895). Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' (PubMed:23163895). Inhibits PTPMT1 phosphatase activity (PubMed:24709986). By inhibiting PTPMT1, positively regulates intrinsic apoptosis (PubMed:21262771). May play a role in the formation of neurites during neuronal development (PubMed:29250526). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dual specificity phosphatase 24 (putative); Dual specificity phosphatase inhibitor MK-STYX; Dual specificity protein phosphatase 24; Inactive dual specificity protein phosphatase MK-STYX; Map kinase phosphatase-like protein MK-STYX; Serine/threonine/tyrosine-interacting-like protein 1
基因别名: DUSP24; MK-STYX; MKSTYX; STYXL1
UniProt ID: (Human) Q9Y6J8
Entrez Gene ID: (Human) 51657