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Recommended positive controls: IMR32, mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Japanese Medaka (97%), Xenopus laevis (98%), Dog (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HSMT3; sentrin 2; Sentrin-2; Small ubiquitin-related modifier 2; SMT3 homolog 2; SMT3 suppressor of mif two 3 homolog 2; SMT3 supressor of mif two 3 homolog 2; Smt3B; SUMO-2; SUMO-3; ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B
基因别名: HSMT3; Smt3A; SMT3B; SMT3H2; SUMO-2; SUMO2; SUMO3
UniProt ID: (Human) P61956, (Mouse) P61957
Entrez Gene ID: (Human) 6613, (Mouse) 170930