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Invitrogen
SUMO2/SUMO3 Monoclonal Antibody (J.778.2)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-14951
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
J.778.2
抗原
Synthetic peptide from the amino terminus of human SUMO-3
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
25 µg/mL
规格
2.5 µg
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
<0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with recombinant SUMO-1.
靶标信息
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GMP1; HSMT3; Sentrin; sentrin 2; Sentrin-2; Small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 3; SMT3 supressor of mif two 3 homolog 2; Smt3A; Smt3B; SMT3C; SMT3H1; SMT3H3; SUMO-1; SUMO-2; SUMO-3; Ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B; UBL1; unnamed protein product
基因别名: 2810014B19Rik; D10Ertd345e; HSMT3; SMT3A; SMT3B; SMT3H1; SMT3H2; SUMO-2; SUMO-3; SUMO2; SUMO3
UniProt ID: (Human) P61956, (Human) P55854, (Rat) P61959, (Mouse) P61957, (Rat) Q5XIF4, (Mouse) Q9Z172
Entrez Gene ID: (Human) 6613, (Human) 6612, (Rat) 690244, (Mouse) 170930, (Rat) 499417, (Mouse) 20610
protein sumoylation
negative regulation of DNA binding
regulation of protein localization to nucleus
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of transcription from RNA polymerase II promoter
cellular protein localization
negative regulation of transcription, DNA-templated
protein localization to nucleus
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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