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Antibodies Inc
SUR2B Monoclonal Antibody (N323B/20)
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产品信息
73-399
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
N323B/20
抗原
Fusion protein amino acids 1503-1545 of rat SUR2B (accession number Q63563-2) produced recombinantly in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
tissue culture supernatant
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: VHTILTADLV IVMKRGNILE YDTPESLLAQ EDGVFASFVR ADM
靶标信息
SUR2B is a subunit of the ATP-sensitive potassium (K_ATP) channel, which is an important protein complex found in various tissues, including cardiac, smooth muscle, and some neurons. The K_ATP channel is involved in regulating cellular excitability and protecting cells under metabolic stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Sulfonylurea receptor 2; sulfonylurea-binding protein 2; unnamed protein product
基因别名: ABC37; ABCC9; AI414027; AI449286; ATFB12; CANTU; CMD1O; IDMYS; SUR2; SUR2A; SUR2B
UniProt ID: (Human) O60706, (Rat) Q63563, (Mouse) P70170
Entrez Gene ID: (Human) 10060, (Rat) 25560, (Mouse) 20928
nucleotide binding
potassium channel activity
ATP binding
sulfonylurea receptor activity
ATP-activated inward rectifier potassium channel activity
potassium channel regulator activity
ATPase activity
cation-transporting ATPase activity
transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of substances
anion transmembrane-transporting ATPase activity
ion channel binding
macromolecular complex binding
potassium channel activator activity
ABC-type transporter activity
drug binding
syntaxin binding
identical protein binding
ATP-binding cassette (ABC) transporter
MAPK cascade
action potential
blood vessel development
response to hypoxia
heart morphogenesis
vascular process in circulatory system
regulation of transcription from RNA polymerase II promoter
potassium ion transport
response to stress
mitochondrion organization
heart development
skeletal muscle tissue development
blood circulation
regulation of blood pressure
response to xenobiotic stimulus
gene expression
response to activity
fatty acid oxidation
response to ATP
response to potassium ion
cellular response to potassium ion
response to decreased oxygen levels
vasodilation
regulation of membrane potential
response to hydrogen peroxide
negative regulation of apoptotic process
response to estrogen
cellular respiration
negative regulation of blood pressure
ATP metabolic process
fibroblast proliferation
defense response to virus
transmembrane transport
coronary vasculature development
cardiac conduction
cellular response to chemical stress
response to oxygen levels
cellular response to calcium ion
cellular response to ATP
cellular response to xenobiotic stimulus
potassium ion transmembrane transport
circulatory system development
oxygen metabolic process
cardiac muscle cell contraction
regulation of blood vessel diameter
cation transmembrane transport
anion transmembrane transport
inorganic cation transmembrane transport
transport across blood-brain barrier
regulation of potassium ion transmembrane transport
response to peptide
reactive oxygen species biosynthetic process
response to hydrogen sulfide
potassium ion import across plasma membrane
substrate-dependent cell migration, cell contraction
signal transduction
metabolic process
potassium ion import
response to drug
transport
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