Invitrogen

SUZ12 Polyclonal Antibody

Name: SUZ12 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-96806
Availability: InStock

高级验证

查看其他20个SUZ12抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (4)
高级验证 (1)

SUZ12 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 5

SUZ12 Antibody (PA5-96806) in ICC/IF

Immunofluorescence analysis of SUZ12 in C6 cells. Samples were incubated with SUZ12 Polyclonal antibody (Product # PA5-96806) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

SUZ12 Antibody in Immunoprecipitation (IP)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

SUZ12 Antibody — Antibody specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. Loss of signal was observed for target protein in SUZ12 knockout (KO) HeLa cells cell line using Anti-SUZ12 Polyclonal Antibody (Product # PA5-96806). {KO}

Immunogen image

Immunogen Image SUZ12 Polyclonal Antibody

产品信息

PA5-96806

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫细胞化学 (ICC/IF)

1:50-1:100

酶联免疫吸附实验 (ELISA)

1 µg/mL

免疫沉淀 (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 470-739 of human SUZ12 (NP_0561702)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.29 mg/mL

129 µg

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2808608

产品详细信息

Immunogen sequence: CHSRFIFNYV YHPKGARIDV SINECYDGSY AGNPQDIHRQ PGFAFSRNGP VKRTPITHIL VCRPKRTKAS MSEFLESEDG EVEQQRTYSS GHNRLYFHSD TCLPLRPQEM EVDSEDEKDP EWLREKTITQ IEEFSDVNEG EKEVMKLWNL HVMKHGFIAD NQMNHACMLF VENYGQKIIK KNLCRNFMLH LVSMHDFNLI SIMSIDKAVT KLREMQQKLE KGESASPANE EITEEQNGTA NGFSEINSKE KALETDSVSG VSKQSKKQKL; Positive Samples: HeLa, BT-474, MCF-7, 293T; Cellular Location: Nucleus

靶标信息

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

仅用于科研。不用于诊断过程。未经明确授权不得转售。